IV Niagen™ Therapy
Boost Your Levels of NAD+
We’re proud to offer IV Niagen, a pharmaceutical-grade intravenous and injectable formulation that represents a new era in cellular health and NAD-boosting infusions.
Backed by scientific research and designed for a superior patient experience, IV Niagen is an excellent alternative to IV NAD+.
TABLE OF CONTENTS
What is Niagen™?
Niagen, also known as nicotinamide riboside chloride (NRC), is a patented, pharmaceutical-grade natural nutrient that boosts levels of Nicotinamide Adenine Dinucleotide (NAD+). NAD+ is a vital coenzyme found in all living cells that plays a crucial role in metabolism and cellular function.
While some are familiar with the oral supplement Tru Niagen®, Niagen IV is a distinct, pharmaceutical-grade brand formulated specifically for intravenous and injectable use. Niagen IV is available exclusively by prescription at a select number of premium clinics, including The AIM Clinic.
Niagen IV Benefits
By restoring optimal levels of NAD+, IV Niagen therapy can have a profound impact on your cellular health and vitality. Our patients have experienced a wide range of benefits, from enhanced mental clarity to improved physical resilience.
Enhanced Mental Clarity & Focus: By supporting the health of neurons and improving communication within the brain, boosting NAD+ levels can help sharpen focus, improve overall cognitive function, and help improve memory.
Neurological Health: NAD+ plays a crucial role in cellular repair, which can aid in the recovery and maintenance of neurological function, including support for depression, anxiety, and memory difficulty.
Boosted Cellular Energy: As a central molecule in cellular energy production, NAD+ directly enhances your mitochondria's ability to produce fuel. This helps to combat fatigue and significantly increases energy levels and vitality.
Metabolic Health: By boosting metabolic function, NAD+ therapy can improve your body’s efficiency in processing nutrients and storing energy, which may aid in weight management and overall metabolic health.
Supports Healthy Aging: The core function of NAD+ is to repair cellular damage. By replenishing this molecule, we can help reduce age- and stress-related damage, promoting healthier aging and supporting the body's natural anti-aging processes, including stem cell activation and skin health.
Faster Recovery & Rehabilitation: By helping to reduce inflammation and oxidative stress at the cellular level, boosting NAD+ levels can significantly speed up recovery from physical exertion, injury, and illness, aiding in rehabilitation.
Immune System Support: By enhancing the function of immune cells, reducing chronic inflammation, and supporting cellular repair, increasing NAD+ levels help to create a more resilient and effective immune system.
Conditions That May Benefit from Boosting NAD+ levels through IV Niagen
Boosting NAD+ levels through IV Niagen may benefit a range of conditions, particularly those linked to cellular stress, energy depletion, and chronic inflammation. Our experience has shown improvements for patients presenting with the following:
Chronic Fatigue Syndrome (ME/CFS): By supporting mitochondrial function and cellular energy production, increasing NAD+ levels may help alleviate the debilitating fatigue and post-exertional malaise that are hallmarks of this condition.
Fibromyalgia: NAD+ can help combat the widespread pain and hypersensitivity characteristic of fibromyalgia by supporting nerve health and reducing inflammation.
Lyme Disease & Co-infections: NAD+ can support the body's repair processes and combat the persistent inflammation and cellular damage often associated with both post-treatment Lyme disease syndrome and Chronic Lyme disease
Long COVID: As a relatively new but impactful condition, Long COVID is often associated with mitochondrial dysfunction and chronic fatigue. Boosting NAD+ levels helps the body's cells produce energy more efficiently, which can assist in recovery from the debilitating symptoms.
Autoimmunity: By supporting cellular health and reducing inflammation, NAD+ may help manage the symptoms of autoimmune disorders where the immune system mistakenly attacks the body's own tissues.
Neurologic Health: NAD+ is crucial for brain function. Replenishing it may support cognitive function and assist in the recovery from various neurological challenges.
Depression: Boosting NAD+ levels helps improve mood and mental clarity, likely due to its role in cellular energy and neurotransmitter synthesis.
Benefits & Side Effects of Niagen vs NAD+
IV Niagen offers a more efficient and comfortable experience compared to traditional NAD+ IV infusions. A pilot clinical study demonstrated several key advantages:
Superior Efficacy: Niagen IV leads to a 20% increase in NAD+ levels within 24 hours of infusion, with blood NAD+ levels peaking sooner and higher just three hours post-infusion. The Niagen NR molecule is more efficient because it can pass directly through cell membranes, unlike the larger NAD+ molecule, which must be broken down first.
Minimal Side Effects: Traditional NAD+ IVs often cause uncomfortable side effects such as headaches, stomach pain, and nausea. In contrast, the clinical trial on Niagen IV showed it was well-tolerated with minimal side effects. Some users even fell asleep during the infusion.
Faster Infusion Time: Niagen IV infusions can be completed in a fraction of the time, taking 75% less chair time compared to traditional NAD+ IVs, which can take up to four hours.
No Inflammatory Response: The pilot clinical study indicated that traditional NAD+ IVs may trigger an inflammatory response, as evidenced by an elevated white blood cell count. Niagen IV, however, did not cause these changes, suggesting it does not cause the same immune response.
We do still offer NAD+ IV, should a patient prefer it, but based on outcome and side effects our general recommendation is for our patients to take IV Niagen if they are seeking support from NAD+.
IV Niagen Safety & Side Effects
Based on the clinical study by Chromadex, a single intravenous infusion of 500 mg of Niagen (nicotinamide riboside, or NR) was found to be safe for participants. There were no serious adverse events directly linked to the infusion, and any side effects were minor and temporary.
Commonly observed side effects of IV Niagen include:
Infusion site discomfort: Some people may feel pain, discomfort, or a change in temperature at the injection site.
Sensory changes: You might experience tingling in your face, extremities, or throughout your body during the IV..
Mild physical symptoms: Some people have reported mild nausea, muscle tension, headaches, or sinus pressure during the IV.
Changes in energy: Your energy level might change after the infusion.
It is important to remember that every person is unique, so these side effects may or may not apply to you.
How Long Do the Effects of IV Niagen Last?
The effects of an IV Niagen (NAD+) infusion typically last up to two weeks for most individuals. The duration and effectiveness, however, depend on a person's unique metabolic needs and health status.
For a lasting and significant shift in your overall health, a loading phase is often recommended. This usually involves a series of infusions, such as one treatment per week for four weeks. This consistent approach helps to deeply replenish NAD+ levels, leading to more profound and sustained improvements in energy, mental clarity, and cellular function.
Following the initial loading phase, a maintenance protocol is advised for ongoing support, particularly for longevity and chronic health conditions. A common maintenance schedule is one infusion per month. This helps to sustain optimal NAD+ levels and continue to support the body’s natural repair and anti-aging processes.
IV Niagen vs IV NAD+ at The AIM Clinic
Patient Testimonials
Our providers have observed significant benefits for patients undergoing IV Niagen therapy, particularly in areas of energy and mental clarity. This is attributed to the therapy's ability to effectively boost NAD+ levels, which are crucial for mitochondrial function and brain health. Many of our patients with conditions like chronic Lyme disease, long COVID, and concussions report a noticeable improvement in symptoms such as brain fog and fatigue after just a few IV Niagen infusions.
For our wellness patients, we have also seen positive outcomes, including improvements in skin health, memory, athletic performance, and a reduction in inflammation.
A key observation from our experience is the comparison to traditional IV NAD+ therapy. Patients typically report quicker and more profound results with IV Niagen. Even individuals who have had negative or limited responses to IV NAD+ have experienced significant health improvements with IV Niagen, suggesting it may be a more effective and tolerable option for many.
“I felt very relaxed with no anxiety or heart palpitations unlike when I did the NAD+. I noticed on my drive back to Bedford my vision seemed sharper than usual. In a wrap up, I feel all the benefits of NAD+ and experienced none of the side effects. My rating 👍👍 up.”
— G.G.
Experts’ Opinions on Niagen IV
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It is no surprise that preliminary research demonstrates that Niagen IV showcases unparalleled efficiency and quality. Niagen IV not only has the potential to help millions looking to support healthspan, but may also provide an option for those dealing with health-related conditions. We are thrilled at this initial data and look forward to future research as Niagen IV sets a new gold standard in the NAD+ industry.
— Dr. Bal Nandra
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I am pleased that ChromaDex has developed an impeccably pure Niagen IV formulation, which is demonstrating a less stressful experience than NAD+ IV. I am confident that Niagen IV will be the gold-standard IV material used to test NAD+ boosting for health conditions and I look forward to future research.
— Dr. Charles Brenner
What to Expect at IV Niagen Session
A single session of our IV Niagen therapy is quick and efficient, lasting approximately 30-60 minutes with minimal side effects when infusing 500 mg.
After our nurse inserts your IV, you can relax as the drip delivers Niagen into your bloodstream. You may feel more energized immediately after the infusion.
Many patients notice a benefit in energy and mental clarity from their first infusion however we typically recommend at least 4 treatments of 500 mg to help determine overall benefits.
A Typical IV Niagen Protocol at The AIM Clinic
Each individual is evaluated based on their health history, goals, sensitivity, and conditions to help determine the ideal IV Niagen protocol. A typical protocol is 500 mg weekly for 4 weeks and then discussing a maintenance plan based on results. For patients seeking an advanced protocol, 1000 mg weekly for 4 weeks is often recommended.
Contraindications
Medical Conditions to be Considered Before Receiving an Nicotinamide Riboside (NR)
Before administering an NR injection or infusion, your AIM Clinic provider will evaluate whether you’re a candidate based on your health history. Special considerations are given to patients with the following conditions:
Hepatic or renal impairment: Individuals with liver or kidney disease should be carefully evaluated.
History of cancer: It is important to consider any prior cancer diagnoses.
Allergies: Patients who have experienced an unusual or allergic reaction to NR, NAD+, or other forms of vitamin B3 should not receive the infusion.
Pregnancy and lactation: The safety of IV Niagen in pregnant or while breastfeeding individuals has not been established.
Pediatric use: The use of IV Niagen in children has not been studied.
Currently, there are no documented interactions between IV Niagen and other medications.
Intramuscular (IM) Niagen
Intramuscular (IM) Niagen injections are also offered at The AIM Clinic and are a convenient and effective way to boost NAD+ levels. While IM administration offers a more gradual and sustained release of the precursor compared to the immediate systemic boost of an IV infusion, it provides an excellent option for those seeking a quick, in-office or at-home treatment. This method is ideal for regular maintenance, ensuring a consistent supply of NAD+ levels for cellular health.
How NAD+ Helps with Longevity
By replenishing the body's natural levels of NAD+, Niagen helps to power our cells' critical functions that diminish with age. As a key coenzyme in every cell, NAD+ is essential for energy metabolism, DNA repair, and the activation of sirtuins—the "longevity genes" that protect our cells from stress and damage. Through our integrative offerings of IV, IM, and oral Niagen, we can effectively restore NAD+ levels, which supports mitochondrial health, enhances cellular repair, and may lead to improved healthspan by combating the cellular decline associated with aging.
Synergistic Therapies for IV Niagen
We've found that IV Niagen works even better when paired with other targeted therapies. By combining treatments, we can create a powerful synergy that addresses your unique health needs and amplifies the benefits of each therapy.
Hyperbaric Oxygen Therapy (HBOT): For patients needing advanced neurologic and immune support, we find HBOT to be highly beneficial. We often recommend receiving your IV Niagen infusion right after an HBOT session. This strategic timing allows the NAD+ to enter a cellular environment rich with oxygen, which may maximize its effectiveness in supporting brain health and immune function.
IV or IM B12 (Methylcobalamin): For patients needing an extra energy boost, we often pair IV Niagen with a Vitamin B12 injection. Vitamin B12 is essential for energy metabolism and red blood cell formation, making it a great partner with IV Niagen in combating fatigue.
IV Glutathione: When detoxification is a primary concern, we frequently recommend pairing IV Niagen with IV Glutathione which is a master antioxidant that plays a key role in neutralizing toxins.
EBOO Therapy: EBOO (Extracorporeal Blood Oxygenation and Ozonation) is a powerful therapy for immune, detoxification, and longevity support. This treatment purifies the blood and reduces the body's toxic and inflammatory load. By creating a cleaner internal environment, EBOO primes your cells to more effectively utilize the NAD+ delivered by IV Niagen. This powerful combination allows your body to focus its energy on cellular repair and rejuvenation, maximizing the benefits for mitochondrial and neurological health.
IV Ketamine: For patients struggling with depression or chronic pain, IV Ketamine is a powerful synergistic therapy to consider. Ketamine infusions can rapidly alleviate symptoms, while the NAD+ works to support long-term cellular and neurological health, providing a more robust and lasting impact.
Our providers can also recommend oral treatments that are synergistic with your IV Niagen therapy to ensure consistent support for your health goals.
Is IV Niagen Right for You?
IV Niagen is designed for patients seeking an advanced, fast-acting wellness treatment that also promotes healthy-aging. To learn more about this innovative therapy and how it can help you achieve your wellness goals, schedule a consultation with one of our providers.
